目的观察超分割放射治疗非小细胞肺癌的近期疗效和急性反应。方法将入组病例随机分为超分割放疗组和常规放疗组,比较两组治疗的近期疗效和急性反应。结果超分割组有效率(CR+PR)为82.5%,常规组有效率为65.6%。急性反应除放射性食管炎有统计学差异(P<0.05)外,其余差异均无显著性意义。结论非小细胞肺癌超分割放疗的近期疗效优于常规放疗,急性放射反应均可耐受。 Objective To observe the short term efficacy and acute response of hyperfractionated radiotherapy for non-small cell lung cancer. Methods The patients were randomly divided into hyperfraction radiotherapy group and conventional radiotherapy group. The short-term curative effect and acute reaction of the two groups were compared. Results The effective rate of CR + PR was 82.5% and that of conventional group was 65.6%. Acute reactions in addition to radioactive esophagitis were statistically different (P <0.05), the remaining differences were not significant. Conclusion The short-term radiotherapy for non-small cell lung cancer is superior to conventional radiotherapy in the short term, and the acute radiation response can be tolerated.