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[目的]观察六君子汤加味联合西药对根除幽门螺杆菌(Hp)及治疗十二指肠溃疡(DU)的疗效。[方法]采用六君子汤加味联合阿莫西林、胶体果胶铋、泮托拉唑钠、甲硝唑治疗Hp阳性的DU患者178例(治疗组),并与单纯西药治疗158例(对照组)作疗效比较,2组疗程均为1个月。[结果]治疗组在溃疡愈合及Hp转阴方面比对照组效果满意,2组比较差异均有统计学意义(均P<0.01)。[结论]六君子汤加味对Hp根除及DU的治疗具有补气健脾、止血生机,促进溃疡愈合,抑制杀灭Hp的协同作用。
[Objective] To observe the curative effect of Liujunzi Decoction combined with western medicine on eradication of Helicobacter pylori (Hp) and treatment of duodenal ulcer (DU). [Method] A total of 178 Hp-positive DU patients treated with Liujunzi decoction combined with amoxicillin, colloidal bismuth pectin, pantoprazole sodium and metronidazole were selected and treated with western medicine alone for 158 cases (control group ) For efficacy comparison, two groups of treatment are 1 month. [Results] The treatment group was better than the control group in the healing of ulcer and Hp negative conversion. The difference between the two groups was statistically significant (P <0.01). [Conclusion] Liujunzi Decoction has the synergistic effect on Hp eradication and DU treatment with invigorating the spleen, stopping bleeding, promoting ulcer healing and inhibiting Hp killing.