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目的:观察中药石上柏对晚期鼻咽癌的放射增敏作用。方法:选择180例鼻咽癌患者,随机分为A、B、C3组:A组患者仅接受单纯放疗;B组从放疗第l天开始,每日用石上柏30g煎水50mL口服,至放疗结束;C组在疗程的后半段开始服用石上柏。结果:A、B、C组的3年生存率分别为28%、38.5%、39.2%,A组与B、C组比较,差异有统计学意义(P<0.05)。结论:石上柏配合放疗能提高局部晚期鼻咽癌的局控率,并转化为总生存率的受益。
OBJECTIVE: To observe the radiosensitization effect of traditional Chinese medicine ShiBai Bai on advanced nasopharyngeal carcinoma. Methods: One hundred and eighty patients with nasopharyngeal carcinoma were randomly divided into A, B, and C3 groups. The patients in group A received only radiotherapy alone. In group B, from the first day of radiotherapy, End; C group in the second half of the course of taking Shi Shang Bai. Results: The 3-year survival rates of group A, B and C were 28%, 38.5% and 39.2% respectively. There was significant difference between group A and group B and C (P <0.05). Conclusion: The combination of Radix Astragali and radiotherapy can improve the local control rate of locally advanced nasopharyngeal carcinoma and translate into the benefit of overall survival.