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目的对孕妇胎儿作ABO血型不合性贫血诊断的前瞻性研究。方法利用彩色多普勒超声检测胎儿大脑中动脉血流情况,并结合孕妇血型抗体效价,统计综合分析两者与ABO血型不合性贫血的相关性问题。结果实验组与对照组胎儿大脑中动脉血流参数和孕妇血型抗体效价存在较显著统计学差异(P<0.05)。结论利用彩色多普勒超声检测胎儿大脑中动脉血流参数并结合孕妇抗体效价预测胎儿ABO血型不合性贫血具实用可行性。
OBJECTIVE: To prospectively study the diagnosis of fetal unhealthy anemia in pregnant women. Methods The blood flow of fetus middle cerebral artery was detected by color Doppler ultrasonography, and the correlation between the blood group antibody and the ABO blood group anemia was analyzed by statistics. Results The blood flow parameters of fetal middle cerebral artery and the antibody titer of blood group in pregnant women were significantly different between the experimental group and the control group (P <0.05). Conclusion It is feasible and practicable to detect the blood flow parameters of fetus middle cerebral artery by color Doppler ultrasonography and to predict the ABO incompatible anemia in fetus according to the antibody titer of pregnant women.