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前文报道了菊科植物款冬花(Tussilagofarfara L.)中精油成分、倍半萜类、酚类及三萜类化合物的分离和结构鉴定。本次继续报道5个新Oplopane型倍半萜化合物(1~5)的分离和结构鉴定。 取日本产的款冬花干燥花芽5.0kg,室温下用乙醚浸泡1周,乙醚提取液经蒸馏得精油(7.7g)及残渣(64.5g)。部分残渣(23.5g)经硅胶柱层析,正己烷-乙酸乙酯
The previous report reported the separation and structure identification of essential oil components, sesquiterpenoids, phenols, and triterpenoids in the Tussilago farfara L. plant. The separation and structure identification of five new Oplopane-type sesquiterpene compounds (1 to 5) continue to be reported this time. Take a dried flower bud of Japanese coltsfoot, which is 5.0kg, and soaked in ether for 1 week at room temperature. The ether extract is distilled to obtain essential oil (7.7g) and residue (64.5g). Part of the residue (23.5 g) was purified by silica gel column chromatography with n-hexane-ethyl acetate