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目的了解广州市钩端螺旋体病(钩体病)重点流行区域流行病学概况。方法用现场流行病学调查方法和血清学检测,对钩体病重点流行区域内健康人群和相关宿主动物进行检测;采用显微镜凝集试验检测抗体。结果对808份健康人群血清标本及727份鼠血清标本进行检测,发现健康人群钩体抗体阳性率为7.30%(59/808),各调查点人群性别间阳性率差异有统计学意义(χ2=6.487,P<0.05);水网及旱地间人群发病率差异亦有统计学意义(χ2=8.068,P<0.01);鼠类阳性率平均为0.55%,其中褐家鼠为0.47%,黄胸鼠为3.17%。结论钩体病重点流行区域内健康人群和野鼠中存在钩体隐性感染,其感染幅度与该地区钩体病的发病有一定的相关作用。
Objective To understand the prevalence of leptospirosis (leptospirosis) in Guangzhou. Methods The epidemiological investigation method and serological test were used to detect the healthy population and related host animals in the endemic areas of Leptospira disease. The antibody was detected by microscope agglutination test. Results The serum samples from 808 healthy people and 727 serum samples from the healthy people were detected. The positive rate of leptospiral antibody was 7.30% (59/808) in healthy population, and there was significant difference between the sexes at each survey point (χ2 = 6.487, P <0.05). There was also a significant difference in the incidence of the disease between the water network and the dry land (χ2 = 8.068, P <0.01); the average positive rate of the mice was 0.55%, of which Rattus norvegicus was 0.47% 3.17% of rats. Conclusions Leptosporic recessive infection exists in healthy population and wild mice in the endemic areas with leptospirosis, and the infection extent has a certain correlation with the incidence of leptospirosis in this area.