论文部分内容阅读
目的观察丹参酮IIA磺酸钠对脑梗死患者治疗前后的血液流变学、血脂及纤维蛋白原的影响,并探讨其临床疗效。方法将108例脑梗死患者随机分两组,治疗组54例,给予丹参酮IIA磺酸钠及常规基础治疗,疗程4周;对照组54例,给予常规基础治疗,观察两组治疗前后血流变、血脂、纤维蛋白原指标变化。疗效按临床神经功能缺损程度评分(NDS)标准进行量化评定。结果治疗组及对照组治疗前后血液指标、神经功能缺损程度明显改善,治疗组改善较对照组明显(P<0.05)。结论早期使用丹参酮IIA磺酸钠能有效调节脑梗死患者血液黏度、降低血脂水平及纤维蛋白原浓度,改善微循环及神经功能缺损症状。
Objective To observe the effects of sodium tanshinone IIA sulfonate on the hemorheology, blood lipid and fibrinogen in patients with cerebral infarction before and after treatment, and to explore its clinical efficacy. Methods 108 cases of cerebral infarction were randomly divided into two groups, the treatment group of 54 cases, given sodium tanshinone IIA sulfonate and routine basic treatment for 4 weeks; control group of 54 cases, given conventional basic treatment, the two groups before and after treatment to observe the change of blood flow , Blood lipids, fibrinogen index changes. Efficacy according to clinical neurological deficit score (NDS) standards for quantitative assessment. Results Before and after treatment, the blood indexes and neurological deficits in treatment group and control group were significantly improved, and the improvement in treatment group was more obvious than that in control group (P <0.05). Conclusion Early use of sodium tanshinone IIA sulfonate can effectively regulate blood viscosity, reduce blood lipid levels and fibrinogen concentration in patients with cerebral infarction, improve symptoms of microcirculation and neurological deficits.