抗磷脂抗体(a PL)是一组能与含有磷脂结构的抗原物质发生反应的自身抗体,其主要类型包括抗心磷脂抗体(ACA)和狼疮抗凝物(LAC)。a PL广泛作用于全身各大器官、系统,可引起多种病理改变,包括冠状动脉粥样硬化、网状青斑、神经病变、肺高压、不良与妊娠等。妇产科近几年临床研究表明,a PL与复发性流产(RSA)、胎儿生长受限(FGR)、早产、死产、子痫前期、胎儿窘迫、HELLP综合征等病 Anti-phospholipid antibodies (a PL) are a group of autoantibodies that react with antigenic substances that contain phospholipid structures. The major types include anti-cardiolipin antibody (ACA) and lupus anticoagulant (LAC). a PL widely acts on various organs and systems of the whole body and can cause many pathological changes including coronary atherosclerosis, reticuloepithelial lesion, neuropathy, pulmonary hypertension, poor pregnancy and so on. Obstetrics and Gynecology in recent years, clinical studies have shown that a PL and recurrent miscarriage (RSA), fetal growth restriction (FGR), premature birth, stillbirth, preeclampsia, fetal distress, HELLP syndrome and other diseases