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孕甾烷X受体(Pregnane X receptor,PXR)为核受体超家族中NR1I亚家族成员,于肝脏和肠道中广泛表达。该受体作为药物代谢的关键调控......
PEG化脂质体（PEGylated liposomes,PEG-L）在体内重复注射出现“加速血液清除”现象（Accelerated blood clearance phenomenon,ABC phe......
胆汁淤积是由多种原因所致的胆汁酸异常积聚,临床表现为黄疸或黄斑瘤等。胆固醇7α-羟化酶(cholesterol 7α-hydroxylase,CYP7A1)......
