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目的 :探析幽门螺杆菌相关性胃溃疡运用两种三联疗法治疗的临床效果。方法 :选择2013年8月-2014年8月期间我院收治的幽门螺杆菌相关性胃溃疡患者80例为研究对象,随机分为两组,其中给予对照组奥美拉唑+阿莫西林+甲硝唑三联法治疗,而观察组则运用奥美拉唑+阿莫西林+克拉霉素三联法治疗,对两组的治疗总有效率和幽门螺杆菌根除率进行对比。结果 :经过6周治疗,相比较对照组而言,观察组的治疗总有效率和幽门螺杆菌根除率明显较高,组间比较差异有统计学意义(P<0.05)。结论 :临床上运用奥美拉唑+阿莫西林+克拉霉素三联法治疗幽门螺杆菌相关性胃溃疡,能够使幽门螺杆菌根除率提高,使临床症状得到改善,值得推广。
Objective: To investigate the clinical effect of two kinds of triple therapy in Helicobacter pylori associated gastric ulcer. Methods: Eighty patients with Helicobacter pylori-associated gastric ulcer admitted to our hospital from August 2013 to August 2014 were randomly divided into two groups. The patients in the control group received omeprazole plus amoxicillin + Metronidazole triple therapy, while the observation group is the use of omeprazole + amoxicillin + clarithromycin triple therapy, the two groups of total effective rate and Helicobacter pylori eradication rate were compared. Results: After 6 weeks of treatment, the total effective rate of treatment and H. pylori eradication rate in the observation group were significantly higher than those in the control group. There was significant difference between the two groups (P <0.05). Conclusion: The clinical application of omeprazole + amoxicillin + clarithromycin triple therapy for Helicobacter pylori-associated gastric ulcer can improve the eradication rate of Helicobacter pylori and improve the clinical symptoms, which deserves promotion.