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目的通过调查健康体检者Brugada心电图征的发生率,获得中国人Brugada综合征的流行病学资料。方法对连续1069例参加年度健康体检的公务员进行病史、家庭史询问、体检、X线胸片和标准12导联心电图检查,按照欧洲心脏病学会推荐标准筛选出Brugada心电图征。结果排除4例器质性心脏病患者后,共1065例(男性805例,女性260例)入选,年龄18～83平均(38.58±15.26)岁。其中39例有黑史,36例有晕厥史,7例有猝死家族史。共8份心电图符合阳性标准,占总例数7.5‰。所有携带者均为男性,心电图均呈鞍型,其中符合Ⅱ型和Ⅲ型者各4例,1例(N7)有黑和晕厥史。结论Brugada心电图征在中国健康汉族人中并不少见,男性多见,其临床意义有待于进一步随访研究证实。
Objective To investigate the epidemiological data of Brugada syndrome in Chinese by investigating the incidence of Brugada electrocardiogram in healthy subjects. Methods A total of 1069 civil servants who participated in the annual physical examination were investigated for history, family history, physical examination, X-ray and standard 12-lead electrocardiogram. The Brugada electrocardiogram was screened according to the recommended standard of European Society of Cardiology. Results After excluding 4 patients with organic heart disease, a total of 1065 cases (805 males and 260 females) were enrolled. The average age ranged from 18 to 83 years (38.58 ± 15.26 years). Among them, 39 cases had history of blackhead gall, 36 cases had history of syncope, and 7 cases had sudden family history of sudden death. A total of 8 electrocardiogram positive standards, accounting for a total of 7.5 ‰. All carriers were male, electrocardiogram showed saddle type, which meet the type Ⅱ and type Ⅲ in 4 cases each, 1 case (N7) have blackheads and history of syncope. Conclusion The ECG of Brugada is not uncommon among healthy Han people in China. It is more common in males. The clinical significance needs to be confirmed by further follow-up studies.