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目的:观察益木脑液灌肠对肝硬化并发肝性脑病的临床疗效。方法:将64例肝硬化并发肝性脑病患者随机分为治疗组与对照组各32例,两组患者均给予治疗肝性脑病的西医综合疗法,包括限制蛋白饮食、保肝、抗肝性脑病、维持电解质平衡、防止感染等,治疗组在西医常规治疗的基础上加用益木脑液灌肠,每天2次,连用7天;对照组在西医常规治疗的基础上加用乳果糖灌肠,每天2次,连用7天。经过1周治疗后比较两组临床疗效及患者的意识状况、血氨、内毒素变化。结果:治疗组在总有效率、意识状况的改善、血氨及内毒素的下降方面优于对照组,两组比较差异有统计学意义(P<0.05)。结论:益木脑液灌肠对治疗肝性脑病有着显著的效果,在肝性脑病患者临床治疗中,是一种安全有效措施。
Objective: To observe the clinical effect of Yimu brain fluid enema on hepatic cirrhosis with hepatic encephalopathy. Methods: Sixty-four patients with hepatic cirrhosis complicated with hepatic encephalopathy were randomly divided into treatment group (32 cases) and control group (32 cases). Both groups were given Western medicine combined therapy for hepatic encephalopathy, which included protein diet restriction, liver protection and hepatic encephalopathy , To maintain electrolyte balance, prevent infection, the treatment group on the basis of conventional Western medicine plus yinmu brain enema, 2 times a day, once every 7 days; control group on the basis of conventional Western medicine plus milk fructose enema, 2 Times, once every 7 days. After one week of treatment, the clinical efficacy and the patients’ consciousness, blood ammonia and endotoxin were compared. Results: The treatment group was better than the control group in the total effective rate, the improvement of the state of consciousness and the decrease of blood ammonia and endotoxin. There was significant difference between the two groups (P <0.05). Conclusion: Yi Mu Na Xie enema for the treatment of hepatic encephalopathy has a significant effect in the clinical treatment of patients with hepatic encephalopathy, is a safe and effective measures.