论文部分内容阅读
目的:探讨放射治疗与微波热疗联合治疗颈部淋巴结转移癌的临床疗效。方法:对58例颈部淋巴结转移癌患者行单纯放疗和放疗加微波热疗,单纯放疗组:采用直线加速器6 MV-X和12 MeV-E/9 MeV-E治疗,累计肿瘤剂量60 Gy～70 Gy/30次～35次/6周～7周;放疗加微波热疗组:放疗同单纯放疗组,微波热疗采用WE-2102A型微波治疗机对颈部淋巴结转移灶区域局部体外加热。30 min/次,2次/周,6次～8次为1个疗程,治疗结束后3个月进行疗效评价。结果:单纯放疗组CR 31.0%(9/29),放疗加微波组CR 58.6%(17/29),两者之间比较差异有显著性(x~2=4.462,P=0.035);总有效率(CR+PR)单纯放疗组65.5%(19/29),放疗加微波组89.7%(26/29),两者之间差异有显著性(x~2=4.858,P=0.028)。结论:颈部肿瘤转移癌单纯放疗效果差,但放射合并加温治疗可以提高疗效。
Objective: To investigate the clinical effects of radiotherapy and microwave hyperthermia in the treatment of cervical lymph node metastases. Methods: Fifty-eight patients with cervical lymph node metastasis underwent radiotherapy and radiotherapy combined with microwave hyperthermia. The radiotherapy alone group was treated with linear accelerator 6 MV-X and 12 MeV-E / 9 MeV-E. The cumulative tumor dose was 60 Gy ~ 70 Gy / 30 times to 35 times / 6 weeks to 7 weeks; radiotherapy plus microwave hyperthermia group: radiotherapy with radiotherapy alone group, microwave hyperthermia using WE-2102A type microwave treatment machine to local lymph node metastasis regional heating in vitro. 30 min / time, 2 times / week, 6 times to 8 times for a course of treatment, 3 months after the end of treatment efficacy evaluation. Results: CR 31.0% (9/29) in radiotherapy alone group and 58.6% (17/29) in radiotherapy plus microwave group had significant difference (x ~ 2 = 4.462, P = 0.035) 65.5% (19/29) in the radiotherapy alone group and 89.7% (26/29) in the radiotherapy plus microwave group were significantly different between the two groups (x = 2 = 4.858, P = 0.028). Conclusions: Radiotherapy alone has a poor effect on neck cancer metastasis, but radiotherapy combined with warming therapy can improve the curative effect.