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目的分析股动脉介入灌注脲激酶、硫辛酸、前列地尔治疗糖尿病足安全性。方法选取50例糖尿病足介入围治疗期中出现的安全性情况,对其影响因素进行分析及预防。结果均安全完成介入治疗,其中38%患者在围治疗期出现紧张不安情绪,出现血压轻度升高、心率轻度加快,血压明显升高者4例。在介入治疗过程中,血压明显升高并表现出烦躁不安、心率加快2例,均给予地西泮治疗后缓解,未发生1例严重并发症。结论股动脉介入置管灌注脲激酶、硫辛酸、前列地尔治疗糖尿病足是安全有效的,但对介入期的安全性问题进行充分评估和防范至关重要。
Objective To analyze the safety of percutaneous arterial infusion of urokinase, lipoic acid and alprostadil in the treatment of diabetic foot. Methods Fifty cases of diabetic foot intervention during the treatment of the safety situation, its influencing factors were analyzed and prevention. The results were safely completed interventional treatment, of which 38% of patients during the Wai period of nervous anxiety, there was mild blood pressure, mild heart rate, blood pressure was significantly higher in 4 cases. In interventional therapy, blood pressure was significantly increased and showed irritability, heart rate in 2 cases, were given after the relief of diazepam, did not occur in 1 case of serious complications. Conclusion Percutaneous catheter perfusion of urokinase, lipoic acid and alprostadil for the treatment of diabetic foot is safe and effective. However, it is very important to fully assess and prevent the safety of interventional period.