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儿童局灶节段性肾小球硬化(FSGS)近年来有增多趋势,FSGS不仅是一种形态学描述,而且被视为一种临床病理综合征,多表现为肾病综合征,同时伴血尿和高血压,病变呈进行性,可继续发展为弥漫性硬化性肾小球肾炎,25%～30%的FSGS患儿5 a后进展至慢性肾衰竭,对激素治疗效果不理想。因此,早期诊断与及时治疗特别重要。现就原发性FSGS的诊断与治疗策略进行阐述。
Children with focal segmental glomerulosclerosis (FSGS) in recent years there is an increasing trend, FSGS is not only a morphological description, but also as a clinical pathological syndrome, mostly manifested as nephrotic syndrome, with hematuria and Hypertension, progressive lesions, can continue to develop diffuse sclerosing glomerulonephritis, 25% to 30% of children with FSGS after 5 a progression to chronic renal failure, the effect of hormone therapy is not satisfactory. Therefore, early diagnosis and prompt treatment are particularly important. Now on the diagnosis and treatment of primary FSGS strategy described.