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目的对膈下逐瘀汤联合拉米夫定用于乙型肝炎肝硬化治疗的效果进行临床研究。方法 120例乙型肝炎肝硬化患者,根据随机分配原则分为对照组和观察组,各60例。观察组患者应用膈下逐瘀汤和拉米夫定进行治疗,对照组患者则单独服用拉米夫定对化进行治疗。观察比较两组患者在治疗前后肝功能指标及血清学标志物阴转情况。结果观察组患者治疗后肝功能指标及血清学标志物阴转情况优于对照组,差异具有统计学意义(P<0.05)。结论膈下逐瘀汤+拉米夫定对乙型肝炎肝硬化患者的治疗效果显著,能够明显改善患者的肝功能和降低纤维化,临床应用方面价值很高,值得推广应用。
Objective To study the clinical effect of Gexia Zhuyu Decoction combined with lamivudine in the treatment of hepatitis B cirrhosis. Methods A total of 120 patients with hepatitis B cirrhosis were divided into control group and observation group according to the principle of random distribution. Patients in the observation group were treated with Gexia Zhuyu Decoction and lamivudine, while patients in the control group were treated with lamivudine alone. Observe and compare the liver function indexes and serological markers of the two groups before and after treatment. Results After treatment, the liver function indexes and serological markers of patients in the observation group were better than those of the control group, the difference was statistically significant (P <0.05). Conclusion Gexiazhuyutang + lamivudine has a significant therapeutic effect on patients with hepatitis B cirrhosis, can significantly improve liver function and reduce fibrosis in patients with high clinical value, which is worth popularizing and applying.