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亚临床甲状腺功能减退症影响心血管系统,增加冠心病风险的报道近年增多,本文总结流行病学调查认为亚临床甲状腺功能减退症是冠心病的独立危险因素;并从影响血凝、血脂、脂蛋白a、C反应蛋白和同型半胱氨酸等指标探讨其增加血栓性疾病的风险因素;亚临床甲状腺功能减退症还会影响心脏传导功能并见心肌功能受损,以及L-T4激素替代治疗等方面,综述亚临床甲状腺功能减退症对心血管系统的影响。鉴于亚临床甲状腺功能减退症的病理改变具有可逆性,评估亚临床甲状腺功能减退症病人L-T4治疗潜在的益处和危险是必要的。这将为临床医生进行针对性的治疗提供依据。
Subclinical hypothyroidism affects the cardiovascular system and increases the risk of coronary heart disease in recent years, the report summarizes the epidemiological survey that subclinical hypothyroidism is an independent risk factor for coronary heart disease; and from the impact of blood coagulation, lipids, lipids Protein a, C-reactive protein and homocysteine and other indicators to explore their risk factors to increase thrombotic disease; subclinical hypothyroidism will affect cardiac conduction and myocardial function impairment, and L-T4 hormone replacement therapy Etc., review the impact of subclinical hypothyroidism on the cardiovascular system. Given the reversibility of the pathologic changes in subclinical hypothyroidism, it is necessary to assess the potential benefits and risks of L-T4 in patients with subclinical hypothyroidism. This will provide the basis for clinicians targeted treatment.