基于荟萃分析的腹腔镜手术治疗肝囊型包虫病的疗效评价

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目的:探讨腹腔镜手术治疗肝囊型包虫病的疗效。方法:在万方医学、维普、知网、PubMed、ScienceDirect、Web of Science等文献平台以“肝囊型包虫病”、“细粒棘球蚴”、“手术”、“开腹手术”、“腹腔镜”、“微创手术”、“hepatic cystic echinococcosis”、“echinococcosis”,“liver or hepatic”,“laparoscopic or minimal invasive”为关键词检索2010年2月至2020年2月文献。对纳入研究的文献中关于术中指标(如手术时间、出血量)、术后并发症、住院时间、复发率等相关数据进行提取并进行荟萃分析。结果:共纳入文献9篇,其中2篇前瞻性研究,7篇回顾性病例对照研究。共纳入1 031例患者,腹腔镜组272例,开腹组759例。荟萃分析结果显示,术后总并发症发生率腹腔镜组低于开腹组(n OR=1.64,95%n CI:1.10~2.45,n P<0.05),其中切口相关并发症腹腔镜组与开腹组差异有统计学意义(n OR=2.81,95%n CI:1.03~7.70,n P<0.05),腹腔镜组住院时间少于开腹组(n SMD=1.21,95%n CI:0.47~1.96,n P0.05)。n 结论:在严格把握腹腔镜手术适应证的前提下,行腹腔镜手术治疗肝囊型包虫病,术后并发症发生率低、住院时间短。“,”Objective:To explore the curative effect of laparoscopic surgery for hepatic cysticercosis.Methods:Search the literature from February 2010 to February 2020 on literature platforms such as Wanfang Data, VIP, CNKI, Pubmed, ScienceDirect, Web of Science, etc. the key words were “肝囊型包虫病” , “细粒棘球蚴” , “手术” , “开腹手术” , “腹腔镜” , “微创手术” , “ echinococcosis ” , “ liver or hepatic ” , “ laparoscopic or minimal invasive ” . Data on intraoperative indicators (e.g., operation time, bleeding volume), postoperative complications, hospital stay, recurrence rate, etc. in the literature included in the study were extracted and meta-analyzed.Results:A total of 9 articles were included, including 2 prospective studies and 7 retrospective case-control studies. A total of 1031 patients were enrolled, including 272 in the laparoscopic group and 759 in the laparotomy group. The results of the meta-analysis showed that the total postoperative complication rate in the laparoscopic group was lower than that in the laparotomy group (n OR=1.64, 95%n CI: 1.10-2.45, n P<0.05). Incision-related complications in the laparoscopy group and laparotomy group the difference was statistically significant (n OR=2.81, 95%n CI: 1.03-7.70, n P<0.05), and the hospital stay in the laparoscopic group was shorter (n SMD=1.21, 95%n CI: 0.47-1.96, n P0.05).n Conclusions:Under the premise of strictly grasping the indication of laparoscopic surgery, the incidence of complications after laparoscopic surgery is low, the hospitalization time is short.
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