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目的探讨美蓝染色和美蓝+荧光显影联合法检测早期乳腺癌前哨淋巴结的效果。方法选择2013年8月至2014年8月期间北京大学人民医院住院确诊为乳腺癌的患者60例,随机平均分为两组,其中A组30例,年龄(48.25±0.23)岁,采用单纯的美蓝染色检测早期乳腺癌前哨淋巴结;B组30例,采用美蓝+荧光显影联合法检测早期乳腺癌前哨淋巴结,比较两种方法对早期乳腺癌前哨淋巴结的检出率并与两组术后的病理结果进行对比。结果 B组的检出率高于A组的检出率,两组比较差异有统计学意义(P<0.05)。结论采用美蓝+荧光显影联合法检测在早期乳腺癌前哨淋巴结检出率中具有较高的临床应用价值。
Objective To investigate the effect of methylene blue staining and methylene blue combined with fluorescence imaging in the detection of sentinel lymph node in early stage of breast cancer. Methods Sixty patients diagnosed as breast cancer from Peking University People’s Hospital between August 2013 and August 2014 were randomly divided into two groups, including 30 patients in group A (48.25 ± 0.23) years old, Methylene blue staining was used to detect sentinel lymph node in early stage of breast cancer. In group B, 30 cases were diagnosed as sentinel lymph node by early detection of breast cancer with methylene blue and fluorescence imaging. The detection rate of sentinel lymph node The pathological results were compared. Results The detection rate of group B was higher than that of group A, the difference was statistically significant (P <0.05). Conclusions The detection rate of sentinel lymph node in early stage of breast cancer by methylene blue + fluorescence imaging combined detection is of high clinical value.