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目的 研究腹泻型、便秘型IBS和功能性便秘患者直肠肛管测压参数的不同 ,并评价性别和年龄对各项参数的影响。方法 腹泻型IBS( n =18)、便秘型IBS( n =14 )、功能性便秘 ( n =3 0 )和健康对照组 ( n =18) ,通过定点牵拉法进行直肠肛管测压。结果 腹泻型IBS、便秘型IBS、功能性便秘以及健康对照组直肠肛管测压各项压力参数基本无差异 ,但三组患者的诱发RAIR所需的最小气体容量均显著高于健康对照组 ,便秘型IBS和功能性便秘模拟排便时发生矛盾运动的百分比显著高于腹泻型IBS和健康对照组 ;便秘型IBS和功能性便秘组中 ,肛管上部和下部最大紧缩压力 ,以及模拟排便发生矛盾运动的百分比男性均高于女性 ;腹泻型IBS组内男性模拟排便发生矛盾运动的百分比高于女性 ;健康对照组内男性肛管下部静息压力和最大紧缩压力高于女性 ;各组 2 0～ 5 0岁人群和 5 0～ 80岁人群的各项压力参数无显著性差异 ,但功能性便秘组青年组诱发RAIR所需的最小气体容量低于老年组。结论 腹泻型IBS、便秘型IBS和功能性便秘患者的直肠肛管测压各项压力参数无助于这三型功能性肠病的鉴别诊断。男性的直肠肛管测压的多项压力参数显著高于女性 ,男性更易出现模拟排便矛盾运动 ,年龄对直肠肛管测压各项参数无明显影响
Objective To study the difference of rectal anal tube manometry parameters in patients with diarrhea, constipation-type IBS and functional constipation and to evaluate the effect of gender and age on various parameters. Methods Rectal anal canal manometry was performed with diarrhea-type IBS (n = 18), constipation type IBS (n = 14), functional constipation (n = 30) and healthy controls (n = 18). Results The pressure parameters of rectum and anal canal in diarrhea type IBS, constipation type IBS, functional constipation and healthy control group were almost the same, but the minimum gas volume needed to induce RAIR in three groups was significantly higher than that in healthy control group, Constipation IBS and functional constipation simulation defecation contradictory movement was significantly higher than the percentage of diarrhea-type IBS and healthy control group; constipation IBS and functional constipation group, the anal canal upper and lower maximum contractile pressure and simulated defecation contradictions The percentages of exercise were higher in males than in females. Diarrhea-type IBS group had more contractile activity in male simulated defecation than in females. The resting pressure and maximal contraction pressure of male anal canal in healthy control group were higher than those in females. There were no significant differences in stress parameters between the 50-year-old population and the 50-to-80-year-old population, but the minimum gas volume required for RAIR in the functional constipation group was lower than in the elderly group. Conclusions The pressure parameters of rectum anal canal in patients with diarrhea-type IBS, constipation-type IBS and functional constipation do not contribute to the differential diagnosis of these three types of functional bowel disease. Men’s rectal anal pressure measurement of a number of pressure parameters were significantly higher than women, men more prone to contradictory simulation of defecation movement, the age of the rectal anal tube pressure of the parameters had no significant effect