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[目的]了解2002~2004年大汶河主干流域研究区及对照区居民的死亡状况及主要恶性肿瘤的疾病负担。[方法]对大汶河主干流域研究区及对照区进行恶性肿瘤为主的死因回顾性调查,按“ICD-10”对死因资料整理分类,应用YPLL、AYPLL、WYPLL和VYPLL等指标进行分析。[结果]2002~2004年大汶河主干流域肿瘤YPLL率达14.82‰,AYPLL为8.29人年,平均WYPLL为5.89人年,平均VYPLL为1.33人年,居全死因YPLL位次第1位,其SYPLL率显著高于对照区(χ2=156.48,P<0.01);肝癌列主要恶性肿瘤YPLL率第1位;男、女性YPLL位次有所不同,男性SYPLL率普遍高于女性;大汶河主干流域研究区上游SYPLL率显著低于中下游(χ2=948.08,P<0.01)。[结论]肿瘤是大汶河主干流域研究区影响当地居民健康和寿命的最大危害,尤以肝癌为甚;中下游是重点地区,应在该地区开展长期的肿瘤监测和防治研究,努力降低肿瘤的危害。
[Objective] To understand the death status of residents and the disease burden of major malignant tumors in the study area and the control area of Dawenhe River from 2002 to 2004. [Methods] A retrospective investigation was made on the cause of death caused by malignant tumor in the study area and the control area of Dawenhe River. The data of cause of death were collected and classified according to “ICD-10”. The indexes of YPLL, AYPLL, WYPLL and VYPLL were analyzed. [Results] The YPLL rate of tumors in Dawenhe River Basin from 2002 to 2004 was 14.82 ‰, and the AYPLL was 8.29 years. The average WYPLL was 5.89 person-years. The mean VYPLL was 1.33 person-years. (Χ2 = 156.48, P <0.01). The incidence of YPLL was the highest in primary malignant tumor of liver cancer. The rank of YPLL in male and female was different. The prevalence of SYPLL in males was higher than that in females. The SYPLL rate in the upper reaches of the study area was significantly lower than that in the middle and lower reaches (χ2 = 948.08, P <0.01). [Conclusion] The tumor is the biggest harm to local health and longevity in Dawenhe River Basin, especially for liver cancer. The middle and lower reaches are the key areas. Long-term cancer surveillance and prevention and treatment should be carried out in this area to reduce the tumor The harm.