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目前趋同认为,再生障碍性贫血(AA)是T细胞介导的,以早期造血干祖细胞为靶目标的自身免疫疾病〔1〕。早期观点和动物模型认为,病毒,尤以乙型、丙型肝炎病毒,EB病毒,以及一些药物、射线是可能是触发AA的因素〔2-3〕。但越来越多的证据表明,有时AA以一种淋巴瘤副肿瘤现象而表现
Convergence of the current view, aplastic anemia (AA) is a T cell mediated early hematopoietic stem and progenitor cells targeted autoimmune diseases [1]. Earlier views and animal models that the virus, especially hepatitis B, hepatitis C virus, Epstein-Barr virus, and some drugs, radiation may be the trigger factor of AA 〔2-3〕. However, there is growing evidence that sometimes AA manifests as a para-tumor of lymphoma