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恶性淋巴瘤(ML)的诊断是当今肿瘤病理学上最感棘手的问题。除形态学和免疫组织化学外,分子水平的诊断已日益显示出重要作用。ML中出现克隆性的免疫球蛋白(Ig)或T细胞受体(TCR)基因重排已为大家所熟悉,并被用于淋巴瘤的辅助诊断。基因重排经典的检测方法...
The diagnosis of malignant lymphoma (ML) is the most troublesome problem in the pathology of today’s tumors. In addition to morphology and immunohistochemistry, the diagnosis at the molecular level has increasingly shown important roles. The presence of clonal immunoglobulin (Ig) or TCR gene rearrangement in ML is well known and used for the adjuvant diagnosis of lymphoma. Gene rearrangement classic detection method...