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目的探讨常规脑脊液细胞学检查在病毒性脑炎诊断中的应用价值。方法选取本院2011年1月~2013年8月间收治的符合病毒性脑炎诊断标准的130例患者作为调查研究对象,使用粟氏FMU-5微型细胞薄片离心沉淀仪提取患者的脑脊液细胞,并在显微镜下观察,回顾性分析患者的常规脑脊液细胞学检查资料。结果本组130例病毒性脑炎患者常规脑脊液细胞学检查阳性例数为119例,阳性率为91.5%,细胞学检查异常者92例,占70.8%,脑脊液白细胞计数≤10×106/L 58例,10×106/L~50×106/L 41例,50×106/L~200×106/L 16例,>200×106/L 4例。结论脑脊液细胞学检查时诊断中枢神经感染性疾病的一项重要指标,操作简便易行,能够提高病毒性脑炎诊断的阳性率,且通过动态监测其变化水平能够对临床疗效进行评估,故可作为病毒性脑炎诊断的首选辅助检查方法。
Objective To investigate the value of routine cerebrospinal fluid cytology in the diagnosis of viral encephalitis. Methods A total of 130 patients with diagnostic criteria of viral encephalitis admitted from January 2011 to August 2013 in our hospital were enrolled in this study. Cerebrospinal fluid (CSF) cells were extracted from patients with FMU-5 microcentrifuge sedimentation, And under the microscope, retrospective analysis of patients with routine cerebrospinal fluid cytology data. Results The positive rate of cerebrospinal fluid cytology in 130 patients with viral encephalitis was 119, the positive rate was 91.5%, the abnormal cytology was 92 (70.8%), the cerebrospinal fluid leukocyte count was less than 10 × 106 / L Cases, 10 × 106 / L ~ 50 × 106 / L in 41 cases, 50 × 106 / L ~ 200 × 106 / L in 16 cases,> 200 × 106 / L in 4 cases. Conclusions CSF CSF cytology examination of an important indicator of CNS infectious diseases, easy to operate, can improve the positive rate of viral encephalitis diagnosis, and through the dynamic monitoring of changes in the level of clinical efficacy can be assessed, it can be As the preferred method of diagnosis of viral encephalitis check.