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大肠杆菌(Escherichia coli)是重要的肠道菌群,致病性大肠杆菌也是引起许多肠内、肠外疾病的罪魁祸首。近些年大肠杆菌耐药现象尤为严重,尤其是多重耐药菌株的出现,在致病性大肠杆菌的预防、控制和治疗上带来巨大困难,给我国养殖业带来巨大的经济损失,同时也对人类的健康造成潜在的威胁。因此,大肠杆菌毒力因子和耐药基因之间关系的研究也是近年来研究的重点问题之一。文章将从毒力因子和细菌耐药性方面阐述研究进展,探讨有效的预防和控制该细菌引起疾病的方法。
Escherichia coli is an important intestinal flora, and pathogenic Escherichia coli is also the culprit causing many intestinal and parenteral diseases. Escherichia coli resistance is particularly serious in recent years, especially the emergence of multi-drug resistant strains, causing great difficulties in the prevention, control and treatment of pathogenic E. coli, bringing huge economic losses to our country’s aquaculture industry. Meanwhile, It also poses a potential threat to human health. Therefore, the relationship between E.coli virulence factors and drug resistance genes is also one of the key issues in recent years. The article will elaborate the research progress from virulence factor and bacterial resistance, and discuss the effective ways to prevent and control the disease caused by the bacteria.