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目的了解广州地区人群血脂分布特征,为血脂异常防治工作提供依据。方法以2015年在广州市番禺疗养院体检中心接受体检的9 778例受检者为研究对象,根据不同年龄段分为6组,收集其血清总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)等指标,分析各年龄段人群血脂水平和血脂异常患病率。结果受检人群TC、TG、HDL-C和LDL-C总体均值分别为5.15 mmol/L、1.55 mmol/L、1.46 mmol/L和3.31 mmol/L,总体标化均值分别为4.96 mmol/L、1.43 mmol/L、1.47 mmol/L和3.18 mmol/L;男、女性各项指标总体均值差异均有统计学意义(P<0.05)。人群血脂异常总患病率为30.03%,总标化患病率为24.69%;其中,男、女性总标化患病率分别为25.14%和20.69%,差异有统计学意义(P<0.05)。男、女性及总体患病率有随年龄的增长呈先升后降趋势(χ2=114.47、23.26、121.46,P<0.01)。结论广州地区人群血脂异常患病率随年龄增大而上升,50岁以上人群患病率较高。
Objective To understand the distribution characteristics of blood lipids in Guangzhou population and provide basis for the prevention and treatment of dyslipidemia. Methods A total of 9 778 subjects undergoing physical examination in the medical center of Panyu Sanatorium in Guangzhou were enrolled in this study. The patients were divided into 6 groups according to different age groups. The levels of total cholesterol (TC), triglyceride (TG) (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were measured to analyze the prevalence of dyslipidemia and lipid levels in all age groups. Results The overall mean values of TC, TG, HDL-C and LDL-C in the subjects were 5.15 mmol / L, 1.55 mmol / L, 1.46 mmol / L and 3.31 mmol / L, 1.43 mmol / L, 1.47 mmol / L and 3.18 mmol / L, respectively. There was significant difference between male and female in overall mean (P <0.05). The total prevalence of dyslipidemia in the population was 30.03% and the total standardized prevalence was 24.69%. Among them, the prevalences of total standardization of male and female were 25.14% and 20.69%, respectively, with significant difference (P <0.05) . The prevalence of males, females and overall prevalence increased first and then decreased with age (χ2 = 114.47,23.26,121.46, P <0.01). Conclusion The prevalence of dyslipidemia in Guangzhou population increases with age, and the prevalence is higher in people over 50 years old.