论文部分内容阅读
目的评估伍德灯(Wood灯)和共聚焦激光扫描显微镜(CLSM)在部分皮肤浅部真菌感染诊断中的应用价值。方法选取满足所选病种临床诊断标准和研究收录标准的病例,取典型部位依次行Wood灯、CLSM和直接镜检,记录结果,行统计学分析。结果本研究共纳入符合标准的患者383例,其中花斑癣82例,马拉色菌毛囊炎34例,头癣30例,手癣34例,足癣54例,体癣41例,股癣49例,甲真菌病59例。383例病例中,Wood灯检测有144例阳性,阳性率37.60%;CLSM检测有241例阳性,阳性率62.92%;直接镜检有308例阳性,阳性率80.42%。结论 Wood灯在花斑糠疹、马拉色菌毛囊炎和头癣诊断中具有较好特异性和敏感性,在手足体股癣和甲真菌病中较差;CLSM在手足体股癣诊断中的特异性和敏感性均较好,在花斑糠疹、马拉色菌毛囊炎、头癣和甲真菌病中特异性良好,敏感性不足。
Objective To evaluate the value of wood lamp and confocal laser scanning microscopy (CLSM) in the diagnosis of partial superficial fungal infections. Methods Selected cases to meet the clinical diagnosis of selected diseases and research included criteria cases, taking the typical parts of the line followed by Wood lamp, CLSM and direct microscopic examination, record the results of statistical analysis. Results A total of 383 eligible patients were included in this study. Among them, 82 were pollinosis, 34 were Malassezia folliculitis, 30 were tinea capitis, 34 were hand ringworm, 54 were tinea pedis, 41 were ringworm, 49 cases, onychomycosis 59 cases. Of the 383 cases, 144 were positive for Wood Light, with a positive rate of 37.60%; 241 were positive for CLSM, and 62.92% for CLSM; 308 were positive for direct microscopy, and the positive rate was 80.42%. Conclusion Wood lamp has good specificity and sensitivity in the diagnosis of pityriasis pityriasis, malassezia folliculitis and tinea capitis, and is poor in tinea corporis and onychomycosis. In the diagnosis of tinea corporis The specificity and sensitivity are good, in the pityriasis versicolor, Malassezia folliculitis, tinea capitis and onychomycosis in the good specificity, lack of sensitivity.