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目的观察腺苷蛋氨酸联合门冬氨钾镁治疗小儿重度黄疸性肝炎的疗效。方法将210例小儿重度黄疸性肝炎患者随机分为观察组和对照组各105例。观察组采用腺苷蛋氨酸联合门冬氨钾镁治疗,对照组采用异甘草酸镁治疗,比较2组治疗效果。结果观察组的总有效率为94.3%高于对照组的83.8%,差异有统计学意义(P<0.05)。治疗后观察组各临床症状改善情况优于对照组,差异有统计学意义(P<0.05)。2组患者接受治疗后均无严重不良反应发生。结论腺苷蛋氨酸联合门冬氨钾镁治疗小儿重度黄疸性肝炎能有效改善患者临床体征,疗效较好,不良反应少,值得临床推广。
Objective To observe the curative effect of adenosylmethionine combined with Aspartame Magnesium and Magnesium in the treatment of severe icteric hepatitis in children. Methods A total of 210 children with severe jaundice hepatitis were randomly divided into observation group (105 cases) and control group (105 cases). The observation group was treated with adenosylmethionine combined with magnesium aspartame, the control group was treated with magnesium isoglycyrrhizinate, and the treatment effect was compared between the two groups. Results The total effective rate of the observation group was 94.3% higher than 83.8% of the control group, the difference was statistically significant (P <0.05). After treatment, the clinical symptoms of the observation group improved better than the control group, the difference was statistically significant (P <0.05). Two groups of patients after treatment did not occur serious adverse reactions. Conclusions Adenosine methionine combined with Aspergillus and magnesium aspartate can effectively improve the clinical signs of patients with severe icteric hepatitis, with good curative effect and few adverse reactions. It is worthy of clinical promotion.