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Th细胞可分化为Th1和Th2细胞亚群 ,分别介导细胞和体液免疫反应。本文从分子水平阐明Th细胞分化的调节机制 ,藉以了解其对许多疾病的治疗及对免疫病理反应干预的重要意义。
Th cells can differentiate into Th1 and Th2 cell subsets that mediate cellular and humoral immune responses, respectively. This article elucidates the regulatory mechanism of Th cell differentiation at the molecular level in order to understand its significance for the treatment of many diseases and the intervention of immunopathological responses.